Product Data Sheet
Nepaprazole
Catalog No. A68381
Nepaprazole is a proton pump inhibitor that targets H+/K+-ATPase activity, significantly reducing gastric acid secretion. It demonstrates inhibitory effects in isolated rabbit gastric mucosal microsomes with IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. This compound is primarily utilized in research related to peptic ulcer diseases, providing insights into gastric acid regulation and potential therapeutic interventions.
Chemical Information
| Catalog Num | A68381 |
|---|---|
| M. Wt | 341.43 |
| Formula | C18H19N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 156601-79-5 |
| Synonyms | rel-TY-11345 free base |
| SMILES | O=S(C1=NC2=CC=CC=C2N1)[C@@]3([H])C4=NC=CC(OC)=C4CCCC3 |
Biological Activity
| Description | Nepaprazole is a proton pump inhibitor that targets H+/K+-ATPase activity, significantly reducing gastric acid secretion. It demonstrates inhibitory effects in isolated rabbit gastric mucosal microsomes with IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. This compound is primarily utilized in research related to peptic ulcer diseases, providing insights into gastric acid regulation and potential therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
