Product Data Sheet
TP0438836
Catalog No. A68416
TP0438836 is a selective inhibitor of the sodium-glucose cotransporter 1 (SGLT1), demonstrating an IC50 value of 28 nM for human SGLT1 and 7 nM for human SGLT2. This compound is of significant interest in diabetes research, as it may help elucidate the role of glucose absorption in glucose homeostasis and insulin regulation. TP0438836 can be utilized in studies aimed at developing therapeutic strategies for managing diabetes and related metabolic disorders.
Chemical Information
| Catalog Num | A68416 |
|---|---|
| M. Wt | 550.60 |
| Formula | C27H38N2O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 957772-01-9 |
| Synonyms | |
| SMILES | O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)CCNC(NC(CO)(CO)CO)=O)=C(C=C2O)C)O[C@@H]([C@H]([C@@H]1O)O)CO |
Biological Activity
| Description | TP0438836 is a selective inhibitor of the sodium-glucose cotransporter 1 (SGLT1), demonstrating an IC50 value of 28 nM for human SGLT1 and 7 nM for human SGLT2. This compound is of significant interest in diabetes research, as it may help elucidate the role of glucose absorption in glucose homeostasis and insulin regulation. TP0438836 can be utilized in studies aimed at developing therapeutic strategies for managing diabetes and related metabolic disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
