Product Data Sheet

S3969

Catalog No. A68432

main product photo
S3969 is a potent and reversible activator of the human epithelial sodium channel (hENaC). With an apparent EC50 of 1.2 μM, S3969 enhances sodium transport across epithelial tissues. This compound serves as a valuable tool for investigating cellular mechanisms related to sodium homeostasis and may be applied in studies of conditions such as hypertension and edema.
Chemical Information
Catalog NumA68432
M. Wt320.45
FormulaC17H24N2O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1027997-01-8
Synonyms
SMILESCC(C)CC(SC1=CNC2=C1C(C)=CC=C2)C(NCCO)=O
Biological Activity
DescriptionS3969 is a potent and reversible activator of the human epithelial sodium channel (hENaC). With an apparent EC50 of 1.2 μM, S3969 enhances sodium transport across epithelial tissues. This compound serves as a valuable tool for investigating cellular mechanisms related to sodium homeostasis and may be applied in studies of conditions such as hypertension and edema.
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