Product Data Sheet
Jingzhaotoxin-III
Catalog No. A68580
Jingzhaotoxin-III is a highly selective blocker of Nav1.5 sodium channels, exhibiting an IC50 of 348 nM with no significant impact on other sodium channel isoforms. This toxin selectively inhibits the activation of cardiac sodium channels, making it a valuable tool for research focused on cardiac physiology and pathophysiology. Its specificity for the cardiac VGSC subtype positions Jingzhaotoxin-III as an important ligand for studies related to cardiovascular health and disease.
Chemical Information
| Catalog Num | A68580 |
|---|---|
| M. Wt | 3919.45 |
| Formula | C174H241N47O46S6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 925463-91-8 |
| Synonyms | β-TRTX-Cj1α |
| SMILES | CC(C(/N=C(O)/C(/N=C(O)/C1CSSCC(N=C(O)C2CCCN2C(C3CCCN34)=O)/C(O)=N/C(/C(O)=N/C(/C(O)=N/C/C(O)=N/C(/C(O)=N/C(/C(O)=N/5)C)CC6=CC=C(O)C=C6)CCCCN)CSSCC(/N=C(O)\C(/N=C(O)/C/N=C(O)/C(N)CC(O)=O)CCC(O)=O)/C(O)=N\C/C(O)=N/C/C(O)=N/C(/C(O)=N/C(/C(O)=N/C(/C(O)=N/C(/C |
Biological Activity
| Description | Jingzhaotoxin-III is a highly selective blocker of Nav1.5 sodium channels, exhibiting an IC50 of 348 nM with no significant impact on other sodium channel isoforms. This toxin selectively inhibits the activation of cardiac sodium channels, making it a valuable tool for research focused on cardiac physiology and pathophysiology. Its specificity for the cardiac VGSC subtype positions Jingzhaotoxin-III as an important ligand for studies related to cardiovascular health and disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
