Product Data Sheet

Ceratotoxin-2

Catalog No. A68585

main product photo
Ceratotoxin-2 is a potent blocker of voltage-gated sodium channels, exhibiting IC50 values of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively. This compound is valuable for investigating sodium channel-related physiological processes and studying disorders associated with sodium channel dysfunction. Its high specificity makes it an essential tool for research in neurobiology and pharmacology, facilitating the development of targeted therapies.
Chemical Information
Catalog NumA68585
M. Wt4092.67
FormulaC177H260N52O49S6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.880885-98-3
SynonymsCcoTx2; β-TRTX-cm1b
SMILES
Biological Activity
DescriptionCeratotoxin-2 is a potent blocker of voltage-gated sodium channels, exhibiting IC50 values of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively. This compound is valuable for investigating sodium channel-related physiological processes and studying disorders associated with sodium channel dysfunction. Its high specificity makes it an essential tool for research in neurobiology and pharmacology, facilitating the development of targeted therapies.
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