Product Data Sheet

Nav1.8-IN-19

Catalog No. A68645

main product photo
Nav1.8-IN-19 is a selective inhibitor of the voltage-gated sodium channel Nav1.8, exhibiting an IC50 of 0.44 nM in HEK293 cells. This compound is instrumental for research focused on nociception and pain pathways, making it a valuable tool for investigating pain modulation and related therapeutic strategies.
Chemical Information
Catalog NumA68645
M. Wt479.48
FormulaC21H20F3N5O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3003829-05-5
Synonyms
SMILESNS(=O)(C1=NC=CC(NC(C2=CC3=C(N=C2N4CCC(F)([C@H](C4)C)F)C=CC(F)=C3)=O)=C1)=O
Biological Activity
DescriptionNav1.8-IN-19 is a selective inhibitor of the voltage-gated sodium channel Nav1.8, exhibiting an IC50 of 0.44 nM in HEK293 cells. This compound is instrumental for research focused on nociception and pain pathways, making it a valuable tool for investigating pain modulation and related therapeutic strategies.
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