Product Data Sheet

N-Depropylpropafenone

Catalog No. A68650

main product photo
N-Depropylpropafenone is a sodium channel blocker and an active metabolite of Propafenone, produced primarily by the CYP450 enzyme system, particularly CYP2D6. It inhibits sodium ion channels, leading to a reduction in myocardial conduction velocity and displaying antiarrhythmic properties. This compound is valuable in the study of cardiac physiology and the mechanisms of arrhythmias.
Chemical Information
Catalog NumA68650
M. Wt299.36
FormulaC18H21NO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.86383-21-3
Synonyms
SMILESO=C(CCC1=CC=CC=C1)C2=C(OCC(CN)O)C=CC=C2
Biological Activity
DescriptionN-Depropylpropafenone is a sodium channel blocker and an active metabolite of Propafenone, produced primarily by the CYP450 enzyme system, particularly CYP2D6. It inhibits sodium ion channels, leading to a reduction in myocardial conduction velocity and displaying antiarrhythmic properties. This compound is valuable in the study of cardiac physiology and the mechanisms of arrhythmias.
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