Product Data Sheet
PF-05105679
Catalog No. A68712
PF-05105679 is a selective antagonist of the transient receptor potential melastatin 8 (TRPM8) channel, exhibiting an IC50 of 103 nM. This compound demonstrates promising biological activity in modulating cold-related pain pathways. It is suitable for research applications investigating the role of TRPM8 in nociception and pain management strategies.
Chemical Information
| Catalog Num | A68712 |
|---|---|
| M. Wt | 428.45 |
| Formula | C26H21FN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1398583-31-7 |
| Synonyms | |
| SMILES | O=C(O)C1=CC=CC(CN([C@@H](C2=CC=C(F)C=C2)C)C(C3=CC4=CC=CC=C4N=C3)=O)=C1 |
Biological Activity
| Description | PF-05105679 is a selective antagonist of the transient receptor potential melastatin 8 (TRPM8) channel, exhibiting an IC50 of 103 nM. This compound demonstrates promising biological activity in modulating cold-related pain pathways. It is suitable for research applications investigating the role of TRPM8 in nociception and pain management strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
