Product Data Sheet
SB 452533
Catalog No. A68750
SB 452533 is a potent and selective antagonist of the TRPV1 ion channel. It demonstrates a pKb of 7.8, indicating strong binding affinity and inhibitory activity. This compound is primarily utilized in research applications related to pain modulation and inflammation, offering insights into the role of TRPV1 in nociception and sensory neurons. SB 452533 is an essential tool for studying pain pathways and developing potential analgesic therapies.
Chemical Information
| Catalog Num | A68750 |
|---|---|
| M. Wt | 376.29 |
| Formula | C18H22BrN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 459429-39-1 |
| Synonyms | |
| SMILES | O=C(NCCN(CC)C1=CC=CC(C)=C1)NC2=CC=CC=C2Br |
Biological Activity
| Description | SB 452533 is a potent and selective antagonist of the TRPV1 ion channel. It demonstrates a pKb of 7.8, indicating strong binding affinity and inhibitory activity. This compound is primarily utilized in research applications related to pain modulation and inflammation, offering insights into the role of TRPV1 in nociception and sensory neurons. SB 452533 is an essential tool for studying pain pathways and developing potential analgesic therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
