Product Data Sheet
Resolvin D2-d5
Catalog No. A68762
Resolvin D2-d5 is a deuterium-labeled derivative of Resolvin D2, a metabolite of docosahexaenoic acid (DHA). This compound exhibits significant anti-inflammatory and anti-infective properties, primarily by regulating leukocyte activity and modulating responses to microbial sepsis. Additionally, Resolvin D2 serves as a potent inhibitor of TRPV1 and TRPA1 channels in primary sensory neurons, with IC50 values of 0.1 nM and 2 nM, respectively. It is valuable for research applications focusing on inflammatory responses and pain pathways.
Chemical Information
| Catalog Num | A68762 |
|---|---|
| M. Wt | 381.52 |
| Formula | C22H27D5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1881277-33-3 |
| Synonyms | RvD2-d5 |
| SMILES | [2H]C(C([2H])([2H])[2H])(/C=C\C[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CCC(O)=O)O)O)O)[2H] |
Biological Activity
| Description | Resolvin D2-d5 is a deuterium-labeled derivative of Resolvin D2, a metabolite of docosahexaenoic acid (DHA). This compound exhibits significant anti-inflammatory and anti-infective properties, primarily by regulating leukocyte activity and modulating responses to microbial sepsis. Additionally, Resolvin D2 serves as a potent inhibitor of TRPV1 and TRPA1 channels in primary sensory neurons, with IC50 values of 0.1 nM and 2 nM, respectively. It is valuable for research applications focusing on inflammatory responses and pain pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
