Product Data Sheet
TRPA1 agonist-3
Catalog No. A68775
TRPA1 Agonist-3 is a selective agonist for the TRPA1 ion channel, displaying EC50 values of 50.05 μM for human TRPA1 and 314.04 μM for mouse TRPA1. This compound does not activate other transient receptor potential channels, including hTRPV1 and hTRPM8. TRPA1 Agonist-3 has demonstrated efficacy in alleviating inflammatory pain in mouse models, operating through a channel desensitization mechanism, making it a valuable tool for studying pain pathways and TRPA1-related pharmacology.
Chemical Information
| Catalog Num | A68775 |
|---|---|
| M. Wt | 262.37 |
| Formula | C14H18N2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3083086-77-2 |
| Synonyms | |
| SMILES | COCCCNC1=NC(C2=CC=C(C=C2)C)=CS1 |
Biological Activity
| Description | TRPA1 Agonist-3 is a selective agonist for the TRPA1 ion channel, displaying EC50 values of 50.05 μM for human TRPA1 and 314.04 μM for mouse TRPA1. This compound does not activate other transient receptor potential channels, including hTRPV1 and hTRPM8. TRPA1 Agonist-3 has demonstrated efficacy in alleviating inflammatory pain in mouse models, operating through a channel desensitization mechanism, making it a valuable tool for studying pain pathways and TRPA1-related pharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
