Product Data Sheet

TRPV4 agonist-1

Catalog No. A68787

main product photo
TRPV4 agonist-1 is a selective agonist of the transient receptor potential vanilloid 4 (TRPV4) channel, exhibiting an EC50 of 60 nM in human TRPV4 calcium assays. This compound is primarily utilized in research to investigate TRPV4-mediated pathways, including physiological functions like osmosensation and nociception. Its ability to activate TRPV4 makes it valuable for studying various biological processes and potential therapeutic applications related to TRP channels.
Chemical Information
Catalog NumA68787
M. Wt484.93
FormulaC25H23ClF2N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2314467-60-0
Synonyms
SMILESO=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C(F)C=CC=C51.Cl
Biological Activity
DescriptionTRPV4 agonist-1 is a selective agonist of the transient receptor potential vanilloid 4 (TRPV4) channel, exhibiting an EC50 of 60 nM in human TRPV4 calcium assays. This compound is primarily utilized in research to investigate TRPV4-mediated pathways, including physiological functions like osmosensation and nociception. Its ability to activate TRPV4 makes it valuable for studying various biological processes and potential therapeutic applications related to TRP channels.
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