RN-9893 hydrochloride
Catalog No. A68812

RN-9893 hydrochloride is a potent antagonist of the transient receptor potential vanilloid 4 (TRPV4) channel, exhibiting IC50 values of 0.42 μM for human and 0.66 μM for rat TRPV4. This compound is valuable for research focused on TRPV4-related physiological processes and pathologies, including pain sensation and inflammatory responses. Its oral bioactivity makes it suitable for in vivo studies investigating the role of TRPV4 in various biological systems.
Chemical Information
| Catalog Num | A68812 |
|---|---|
| M. Wt | 536.95 |
| Formula | C21H24ClF3N4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2109450-40-8 |
| Synonyms | |
| SMILES | O=S(C(C=C1)=CC=C1NC(C2=C([N+]([O-])=O)C=C(C(F)(F)F)C=C2)=O)(N3CCN(C(C)C)CC3)=O.Cl |
Biological Activity
| Description | RN-9893 hydrochloride is a potent antagonist of the transient receptor potential vanilloid 4 (TRPV4) channel, exhibiting IC50 values of 0.42 μM for human and 0.66 μM for rat TRPV4. This compound is valuable for research focused on TRPV4-related physiological processes and pathologies, including pain sensation and inflammatory responses. Its oral bioactivity makes it suitable for in vivo studies investigating the role of TRPV4 in various biological systems. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


