TRPV4 antagonist 3
Catalog No. A68824

TRPV4 antagonist 3 is a selective antagonist of the TRPV4 ion channel, demonstrating a pIC50 value of 8.4. This compound effectively inhibits TRPV4-mediated calcium influx, making it a valuable tool for investigating the physiological roles of TRPV4 in various biological processes. It has potential applications in pain research, inflammation studies, and the exploration of therapeutic strategies for TRPV4-related disorders.
Chemical Information
| Catalog Num | A68824 |
|---|---|
| M. Wt | 470.44 |
| Formula | C20H18F4N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2681273-35-6 |
| Synonyms | |
| SMILES | O=S(C1=CC=C(C#N)C=C1C(F)(F)F)(NCC[C@](C)(N)COC2=CC=C(C#N)C(F)=C2)=O |
Biological Activity
| Description | TRPV4 antagonist 3 is a selective antagonist of the TRPV4 ion channel, demonstrating a pIC50 value of 8.4. This compound effectively inhibits TRPV4-mediated calcium influx, making it a valuable tool for investigating the physiological roles of TRPV4 in various biological processes. It has potential applications in pain research, inflammation studies, and the exploration of therapeutic strategies for TRPV4-related disorders. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


