Product Data Sheet
JYL-273 analog-1
Catalog No. A68840
JYL-273 analog-1 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) ion channel, exhibiting a Ki value of 10.8 nM. This compound demonstrates significant analgesic activity, with an ED50 of 1.0 mg/kg in the PBQ-induced writhing test. JYL-273 analog-1 is suitable for investigations into pain mechanisms and the development of analgesic therapies.
Chemical Information
| Catalog Num | A68840 |
|---|---|
| M. Wt | 500.69 |
| Formula | C28H40N2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 289902-71-2 |
| Synonyms | |
| SMILES | CC(C)(C)C(OCC(CNC(NCC1=CC=C(O)C(OC)=C1)=S)CC2=CC=C(C(C)(C)C)C=C2)=O |
Biological Activity
| Description | JYL-273 analog-1 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) ion channel, exhibiting a Ki value of 10.8 nM. This compound demonstrates significant analgesic activity, with an ED50 of 1.0 mg/kg in the PBQ-induced writhing test. JYL-273 analog-1 is suitable for investigations into pain mechanisms and the development of analgesic therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
