Product Data Sheet

TRPV4/TRPA1-IN-1

Catalog No. A68846

main product photo
TRPV4/TRPA1-IN-1 is a selective inhibitor of the TRPV4 and TRPA1 channels, effectively blocking calcium influx mediated by these targets. This compound demonstrates significant efficacy in reducing pain behaviors in mouse models, particularly in trigeminal stimulation and acute pancreatitis contexts. TRPV4/TRPA1-IN-1 is valuable for research focused on pain modulation and inflammation associated with acute pancreatitis.
Chemical Information
Catalog NumA68846
M. Wt399.56
FormulaC25H25N3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1532515-60-8
Synonyms
SMILESN1=C(SC=C1C=2C=CC=CC2)NC3=CC=C(C=C3)CCN(C)CC=4C=CC=CC4
Biological Activity
DescriptionTRPV4/TRPA1-IN-1 is a selective inhibitor of the TRPV4 and TRPA1 channels, effectively blocking calcium influx mediated by these targets. This compound demonstrates significant efficacy in reducing pain behaviors in mouse models, particularly in trigeminal stimulation and acute pancreatitis contexts. TRPV4/TRPA1-IN-1 is valuable for research focused on pain modulation and inflammation associated with acute pancreatitis.
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