Product Data Sheet
GSK2332255B
Catalog No. A68861
GSK2332255B is a highly selective antagonist of TRPC3 and TRPC6 channels, exhibiting IC50 values of 5 nM and 4 nM, respectively, for rat TRPC3 and TRPC6. This compound demonstrates over 100-fold selectivity for TRPC3 and TRPC6 compared to other calcium-permeable channels. GSK2332255B is valuable for research applications investigating the role of TRPC channels in various physiological and pathological processes.
Chemical Information
| Catalog Num | A68861 |
|---|---|
| M. Wt | 411.88 |
| Formula | C18H19ClFN3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1366233-41-1 |
| Synonyms | |
| SMILES | O=C(C1=C(Cl)SC(NC2=C(F)C=C(OCO3)C3=C2)=N1)N4C(C)C(C)CCC4 |
Biological Activity
| Description | GSK2332255B is a highly selective antagonist of TRPC3 and TRPC6 channels, exhibiting IC50 values of 5 nM and 4 nM, respectively, for rat TRPC3 and TRPC6. This compound demonstrates over 100-fold selectivity for TRPC3 and TRPC6 compared to other calcium-permeable channels. GSK2332255B is valuable for research applications investigating the role of TRPC channels in various physiological and pathological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
