Product Data Sheet
TRPC3/6-IN-1
Catalog No. A68885
TRPC3/6-IN-1 is a selective blocker of the canonical transient receptor potential channels TRPC3 and TRPC6, exhibiting IC50 values of 1260 nM and 500 nM, respectively. This compound is instrumental for investigating the role of TRPC3 and TRPC6 in cardiac physiology and pathophysiology, particularly in chronic models of heart failure. Its specific inhibitory action makes it a valuable tool for studying the mechanisms underlying cardiovascular diseases.
Chemical Information
| Catalog Num | A68885 |
|---|---|
| M. Wt | 365.45 |
| Formula | C20H19N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 736945-96-3 |
| Synonyms | |
| SMILES | COC1=CC=C(NC2=NC(C(N3CCC4=C(C3)C=CC=C4)=O)=CS2)C=C1 |
Biological Activity
| Description | TRPC3/6-IN-1 is a selective blocker of the canonical transient receptor potential channels TRPC3 and TRPC6, exhibiting IC50 values of 1260 nM and 500 nM, respectively. This compound is instrumental for investigating the role of TRPC3 and TRPC6 in cardiac physiology and pathophysiology, particularly in chronic models of heart failure. Its specific inhibitory action makes it a valuable tool for studying the mechanisms underlying cardiovascular diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
