Product Data Sheet

Ibuprofen acyl-β-D-glucuronide

Catalog No. A68886

main product photo
Ibuprofen acyl-β-D-glucuronide is a selective antagonist of the TRPA1 ion channel. This compound effectively reduces the calcium response induced by allyl isothiocyanate (AITC), exhibiting an IC50 value of 60 μM. It is a valuable tool for investigating TRPA1-related pathways and for exploring potential therapeutic applications in pain modulation and sensory signal transduction.
Chemical Information
Catalog NumA68886
M. Wt382.40
FormulaC19H26O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.115075-59-7
SynonymsIbuprofen glucuronide
SMILESCC(C(O[C@@H]1O[C@H](C(O)=O)[C@H]([C@@H]([C@H]1O)O)O)=O)C2=CC=C(C=C2)CC(C)C
Biological Activity
DescriptionIbuprofen acyl-β-D-glucuronide is a selective antagonist of the TRPA1 ion channel. This compound effectively reduces the calcium response induced by allyl isothiocyanate (AITC), exhibiting an IC50 value of 60 μM. It is a valuable tool for investigating TRPA1-related pathways and for exploring potential therapeutic applications in pain modulation and sensory signal transduction.
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SHIPPING AND STORAGE
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