Product Data Sheet
URAT1&XO inhibitor 3
Catalog No. A68910
URAT1&XO Inhibitor 3 is a potent inhibitor of both xanthine oxidase (XO) and urate transporter 1 (URAT1), with IC50 values of 35 nM and 31 nM, respectively. This compound exhibits significant potential as an orally active anti-gout agent, demonstrating favorable pharmacological and pharmacokinetic properties. Additionally, URAT1&XO Inhibitor 3 has been shown to have in vivo safety, making it a valuable tool for research in the management of hyperuricemia and gout-related disorders.
Chemical Information
| Catalog Num | A68910 |
|---|---|
| M. Wt | 297.24 |
| Formula | C16H8FNO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2089040-93-5 |
| Synonyms | |
| SMILES | O=C(O)C1=CC=C(C2=C(OC(F)=C3)C3=CC(C#N)=C2)C=C1O |
Biological Activity
| Description | URAT1&XO Inhibitor 3 is a potent inhibitor of both xanthine oxidase (XO) and urate transporter 1 (URAT1), with IC50 values of 35 nM and 31 nM, respectively. This compound exhibits significant potential as an orally active anti-gout agent, demonstrating favorable pharmacological and pharmacokinetic properties. Additionally, URAT1&XO Inhibitor 3 has been shown to have in vivo safety, making it a valuable tool for research in the management of hyperuricemia and gout-related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
