Product Data Sheet

UE2316

Catalog No. A68931

main product photo
UE2316 is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1). It has been shown to significantly enhance glucose tolerance and insulin sensitivity in uremic rat models. Additionally, UE2316 has been associated with the exacerbation of hepatic fibrosis in mice. This compound is utilized in research pertaining to metabolic disorders, including hepatic fibrosis, uremia, and diabetes mellitus.
Chemical Information
Catalog NumA68931
M. Wt389.87
FormulaC19H17ClFN3OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1274933-58-2
Synonyms
SMILESO=C(C1=CSC(=C1)C=2C=NNC2)N3CCC(F)(C=4C=CC=CC4Cl)CC3
Biological Activity
DescriptionUE2316 is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1). It has been shown to significantly enhance glucose tolerance and insulin sensitivity in uremic rat models. Additionally, UE2316 has been associated with the exacerbation of hepatic fibrosis in mice. This compound is utilized in research pertaining to metabolic disorders, including hepatic fibrosis, uremia, and diabetes mellitus.
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