Product Data Sheet
11β-HSD1-IN-8
Catalog No. A68941
11β-HSD1-IN-8 is an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β HSD1) with an IC50 value of 2.3 μM against human 11β HSD1. This compound is of significant interest for research into metabolic disorders, particularly diabetes, and its potential impact on cognitive decline. By modulating the enzymatic activity of 11β HSD1, this reagent can facilitate studies aimed at understanding its role in glucocorticoid metabolism and related pathophysiological conditions.
Chemical Information
| Catalog Num | A68941 |
|---|---|
| M. Wt | 247.17 |
| Formula | C10H8F3NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 386704-15-0 |
| Synonyms | |
| SMILES | COC(=O)CC(=O)C1=CN=C(C=C1)C(F)(F)F |
Biological Activity
| Description | 11β-HSD1-IN-8 is an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β HSD1) with an IC50 value of 2.3 μM against human 11β HSD1. This compound is of significant interest for research into metabolic disorders, particularly diabetes, and its potential impact on cognitive decline. By modulating the enzymatic activity of 11β HSD1, this reagent can facilitate studies aimed at understanding its role in glucocorticoid metabolism and related pathophysiological conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
