Product Data Sheet

11β-HSD1-IN-1

Catalog No. A68943

main product photo
11β-HSD1-IN-1 is a selective inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1) with an IC50 value of 52 nM. It has demonstrated biological activity relevant to modulating corticosteroid metabolism, making it a valuable tool in studies related to various metabolic and inflammatory disorders. This compound is primarily utilized in research applications focused on pain management and related therapeutic areas.
Chemical Information
Catalog NumA68943
M. Wt399.77
FormulaC18H14ClF4N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1203956-47-1
Synonyms
SMILESCC(C1=NN=C(C2=CC=C(F)C=C2Cl)N1C)(C)OC3=C(F)C=C(F)C=C3F
Biological Activity
Description11β-HSD1-IN-1 is a selective inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1) with an IC50 value of 52 nM. It has demonstrated biological activity relevant to modulating corticosteroid metabolism, making it a valuable tool in studies related to various metabolic and inflammatory disorders. This compound is primarily utilized in research applications focused on pain management and related therapeutic areas.
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