Product Data Sheet
BVT-116429
Catalog No. A68945
BVT-116429 is a selective inhibitor of 11β-HSD1, a key enzyme involved in cortisol metabolism. This compound has been shown to enhance adiponectin levels and improve glucose homeostasis in diabetic mouse models. In studies involving diabetic KKAy mice, BVT-116429 effectively reduced basal insulin levels and fasting blood glucose levels after 10 days of treatment, demonstrating a potential therapeutic role in the management of metabolic disorders.
Chemical Information
| Catalog Num | A68945 |
|---|---|
| M. Wt | 320.31 |
| Formula | C13H12F4N2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 870710-02-4 |
| Synonyms | |
| SMILES | C[C@@H](C1=C(C=CC=C1)F)NC(S[C@@](C)2C(F)(F)F)=NC2=O |
Biological Activity
| Description | BVT-116429 is a selective inhibitor of 11β-HSD1, a key enzyme involved in cortisol metabolism. This compound has been shown to enhance adiponectin levels and improve glucose homeostasis in diabetic mouse models. In studies involving diabetic KKAy mice, BVT-116429 effectively reduced basal insulin levels and fasting blood glucose levels after 10 days of treatment, demonstrating a potential therapeutic role in the management of metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
