Product Data Sheet
BI-135585 hydrate
Catalog No. A68958
BI-135585 hydrate is a selective and potent inhibitor of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) with an IC50 of 13 nM. This compound demonstrates greater than 1000-fold selectivity over other hydroxysteroid dehydrogenases, making it a valuable tool for research. BI-135585 hydrate is primarily employed in studies related to type 2 diabetes, where modulation of glucocorticoid metabolism is of interest.
Chemical Information
| Catalog Num | A68958 |
|---|---|
| M. Wt | 478.58 |
| Formula | C28H34N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1374032-89-9 |
| Synonyms | |
| SMILES | CC(C)(O)C[C@@]1(C2=CC=CC=C2)OC(N(CC1)[C@H](C3=CC=C(C4=CC(N(C=C4)C)=O)C=C3)C)=O.O |
Biological Activity
| Description | BI-135585 hydrate is a selective and potent inhibitor of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) with an IC50 of 13 nM. This compound demonstrates greater than 1000-fold selectivity over other hydroxysteroid dehydrogenases, making it a valuable tool for research. BI-135585 hydrate is primarily employed in studies related to type 2 diabetes, where modulation of glucocorticoid metabolism is of interest. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
