Product Data Sheet
S07-1066
Catalog No. A68986
S07-1066 is a selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) that enhances the cytotoxic effects of doxorubicin (DOX). By inhibiting the AKR1C3-mediated reduction of DOX, S07-1066 effectively reverses drug resistance in cells that overexpress this enzyme. This compound is valuable for research applications investigating chemotherapy resistance and potential adjuvant therapies in cancer treatment.
Chemical Information
| Catalog Num | A68986 |
|---|---|
| M. Wt | 325.16 |
| Formula | C16H11Cl2FO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 876625-29-5 |
| Synonyms | |
| SMILES | ClC1=CC(Cl)=CC(C2=CC=C(C3(C(O)=O)CC3)C=C2F)=C1 |
Biological Activity
| Description | S07-1066 is a selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) that enhances the cytotoxic effects of doxorubicin (DOX). By inhibiting the AKR1C3-mediated reduction of DOX, S07-1066 effectively reverses drug resistance in cells that overexpress this enzyme. This compound is valuable for research applications investigating chemotherapy resistance and potential adjuvant therapies in cancer treatment. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
