Product Data Sheet
Odafosfamide
Catalog No. A68995
Odafosfamide is a selective prodrug bis-alkylating agent that is activated by aldehyde-keto reductase 1C3 (AKR1C3). It exhibits potent cytotoxicity in cell lines that express high levels of AKR1C3, demonstrating significant antitumor activity in various cancers, including liver cancer, non-small cell lung cancer, and leukemia. This compound is suitable for use in cancer research to investigate mechanisms of action and therapeutic potential in malignancies characterized by elevated AKR1C3 expression.
Chemical Information
| Catalog Num | A68995 |
|---|---|
| M. Wt | 460.42 |
| Formula | C21H25N4O6P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2097713-69-2 |
| Synonyms | (S)-OBI-3424; (S)-TH-3424; AST-3424 |
| SMILES | C[C@@H](C1=CC(OC2=CC(C(N(C)C)=O)=CC=C2)=C(C=C1)[N+]([O-])=O)OP(N3CC3)(N4CC4)=O |
Biological Activity
| Description | Odafosfamide is a selective prodrug bis-alkylating agent that is activated by aldehyde-keto reductase 1C3 (AKR1C3). It exhibits potent cytotoxicity in cell lines that express high levels of AKR1C3, demonstrating significant antitumor activity in various cancers, including liver cancer, non-small cell lung cancer, and leukemia. This compound is suitable for use in cancer research to investigate mechanisms of action and therapeutic potential in malignancies characterized by elevated AKR1C3 expression. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
