Product Data Sheet

HSD17B13-IN-10

Catalog No. A68996

main product photo
HSD17B13-IN-10 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of 0.01 μM. This compound is valuable in researching liver diseases by modulating steroid metabolism and influencing lipid and glucose homeostasis. Its selective inhibition makes it a critical tool for studying the pathogenic mechanisms underlying hepatic disorders.
Chemical Information
Catalog NumA68996
M. Wt444.40
FormulaC23H19F3N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2576696-23-4
Synonyms
SMILESCC1=CC2=C(C(C3=C(O2)C=C(C=C3)C)NC(C4=CC(CO)=C(NC4=O)C(F)(F)F)=O)C=C1
Biological Activity
DescriptionHSD17B13-IN-10 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of 0.01 μM. This compound is valuable in researching liver diseases by modulating steroid metabolism and influencing lipid and glucose homeostasis. Its selective inhibition makes it a critical tool for studying the pathogenic mechanisms underlying hepatic disorders.
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