Product Data Sheet
HSD17B13-IN-97
Catalog No. A69006
HSD17B13-IN-97 is a highly potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤0.1 µM. This compound holds promise for investigating therapeutic strategies for nonalcoholic fatty liver diseases (NAFLDs), nonalcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its selective inhibition of HSD17B13 makes it a valuable tool for exploring lipid metabolism and liver pathology in preclinical research.
Chemical Information
| Catalog Num | A69006 |
|---|---|
| M. Wt | 458.37 |
| Formula | C22H14F4N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2849338-44-7 |
| Synonyms | |
| SMILES | OC1=C(C(F)(F)F)N=C(C(NC2=CC=CC(N=CN3CC4=CC=CC=C4F)=C2C3=O)=O)C=C1 |
Biological Activity
| Description | HSD17B13-IN-97 is a highly potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤0.1 µM. This compound holds promise for investigating therapeutic strategies for nonalcoholic fatty liver diseases (NAFLDs), nonalcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its selective inhibition of HSD17B13 makes it a valuable tool for exploring lipid metabolism and liver pathology in preclinical research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
