Product Data Sheet

HSD17B13-IN-88

Catalog No. A69092

main product photo
HSD17B13-IN-88 is a potent inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤0.1 μM for estradiol. This compound selectively modulates steroid hormone metabolism and has significant implications for research in metabolic disorders and liver diseases. Its ability to influence estradiol levels makes it a valuable tool for studying hormone-related pathways and therapeutic strategies.
Chemical Information
Catalog NumA69092
M. Wt508.40
FormulaC27H23Cl2N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2770247-93-1
Synonyms
SMILESOC1=C(Cl)C=C(C(NC2=C3C(N=C(C)N([C@H]4[C@H](C5=CC=CC=C5)CC4)C3=O)=C(C)C=C2)=O)C=C1Cl
Biological Activity
DescriptionHSD17B13-IN-88 is a potent inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤0.1 μM for estradiol. This compound selectively modulates steroid hormone metabolism and has significant implications for research in metabolic disorders and liver diseases. Its ability to influence estradiol levels makes it a valuable tool for studying hormone-related pathways and therapeutic strategies.
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