Product Data Sheet

HSD17B13-IN-78

Catalog No. A69099

main product photo
HSD17B13-IN-78 is a selective inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol. This compound is primarily utilized in research focused on nonalcoholic fatty liver disease (NAFLD), aiding in the understanding of lipid metabolism and associated metabolic disorders. HSD17B13-IN-78 serves as an important tool for studying the therapeutic potential of targeting HSD17B13 in liver-related pathologies.
Chemical Information
Catalog NumA69099
M. Wt459.26
FormulaC21H13Cl2FN4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2770246-21-2
Synonyms
SMILESOC1=C(Cl)N=C(C(NC2=CC=CC3=C2C(N(CC4=CC(F)=CC=C4)C=N3)=O)=O)C=C1Cl
Biological Activity
DescriptionHSD17B13-IN-78 is a selective inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol. This compound is primarily utilized in research focused on nonalcoholic fatty liver disease (NAFLD), aiding in the understanding of lipid metabolism and associated metabolic disorders. HSD17B13-IN-78 serves as an important tool for studying the therapeutic potential of targeting HSD17B13 in liver-related pathologies.
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