Product Data Sheet
Finasteride-d9
Catalog No. A69125
Finasteride-d9 is a deuterium-labeled derivative of Finasteride, a potent competitive inhibitor of 5α-reductase, exhibiting an IC50 of 4.2 nM for the type II isoform. This compound demonstrates significantly greater affinity for type II 5α-reductase, being approximately 100 times more selective than for type I. Finasteride-d9 is valuable in research applications focused on benign prostatic hyperplasia (BPH) and androgenic alopecia, facilitating studies on the pharmacokinetics and metabolism of its parent compound.
Chemical Information
| Catalog Num | A69125 |
|---|---|
| M. Wt | 381.60 |
| Formula | C23H27D9N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1131342-85-2 |
| Synonyms | MK-906-d9 |
| SMILES | C[C@@]12[C@](CC[C@@H]2C(NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](NC(C=C4)=O)([H])CC3)C |
Biological Activity
| Description | Finasteride-d9 is a deuterium-labeled derivative of Finasteride, a potent competitive inhibitor of 5α-reductase, exhibiting an IC50 of 4.2 nM for the type II isoform. This compound demonstrates significantly greater affinity for type II 5α-reductase, being approximately 100 times more selective than for type I. Finasteride-d9 is valuable in research applications focused on benign prostatic hyperplasia (BPH) and androgenic alopecia, facilitating studies on the pharmacokinetics and metabolism of its parent compound. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
