Product Data Sheet
CM037
Catalog No. A69335
CM037 is a highly selective and competitive inhibitor of the enzyme ALDH1A1, with an IC50 of 4.6 μM. By blocking the catalytic activity of ALDH1A1, CM037 inhibits the activation of the HIF-1α/VEGF signaling pathway. This reagent is primarily utilized to investigate the role of ALDH1A1 in the regulation of cancer stem cells and angiogenesis, particularly in breast cancer models, highlighting its potential to obstruct tumor angiogenesis and stem cell properties.
Chemical Information
| Catalog Num | A69335 |
|---|---|
| M. Wt | 431.57 |
| Formula | C21H25N3O3S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 896795-60-1 |
| Synonyms | A37 |
| SMILES | O=C1C2=C(N=C(SCC(OCC)=O)N1CCCN3CCCC3)C4=CC=CC=C4S2 |
Biological Activity
| Description | CM037 is a highly selective and competitive inhibitor of the enzyme ALDH1A1, with an IC50 of 4.6 μM. By blocking the catalytic activity of ALDH1A1, CM037 inhibits the activation of the HIF-1α/VEGF signaling pathway. This reagent is primarily utilized to investigate the role of ALDH1A1 in the regulation of cancer stem cells and angiogenesis, particularly in breast cancer models, highlighting its potential to obstruct tumor angiogenesis and stem cell properties. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
