Product Data Sheet
NCT-501 hydrochloride
Catalog No. A69365
NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), demonstrating an IC50 of 40 nM. It exhibits superior selectivity against other ALDH isozymes, as well as various dehydrogenases, with IC50 values greater than 57 μM for hALDH1B1, hALDH3A1, and hALDH2. This compound is valuable for research applications focused on cancer biology, neurodegenerative diseases, and other conditions where ALDH1A1 activity plays a critical role.
Chemical Information
| Catalog Num | A69365 |
|---|---|
| M. Wt | 452.98 |
| Formula | C21H33ClN6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2080306-22-3 |
| Synonyms | |
| SMILES | O=C(N1C)N(C)C2=C(N(CCC(C)C)C(CN3CCN(C(C4CC4)=O)CC3)=N2)C1=O.[H]Cl |
Biological Activity
| Description | NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), demonstrating an IC50 of 40 nM. It exhibits superior selectivity against other ALDH isozymes, as well as various dehydrogenases, with IC50 values greater than 57 μM for hALDH1B1, hALDH3A1, and hALDH2. This compound is valuable for research applications focused on cancer biology, neurodegenerative diseases, and other conditions where ALDH1A1 activity plays a critical role. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
