Product Data Sheet
Adamantanine
Catalog No. A69422
Adamantanine is a potent inhibitor of leucine aminopeptidase, demonstrating an I/S0.5 value of 10.5. It effectively impairs the transport of methionine and leucine in Ehrlich ascites carcinoma cells, with a Ki value of 0.76 mM. Additionally, Adamantanine displays inhibitory effects on the proliferation of P388 lymphocytic leukemia cells, exhibiting an IC50 of greater than 1 mM. This compound serves as a valuable tool for researchers investigating amino acid transport and cancer cell proliferation.
Chemical Information
| Catalog Num | A69422 |
|---|---|
| M. Wt | 195.26 |
| Formula | C11H17NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 42381-05-5 |
| Synonyms | 2-Aminoadamantane-2-carboxylic acid |
| SMILES | OC(C1([C@H]2C[C@H](C3)C[C@@H]1C[C@H]3C2)N)=O |
Biological Activity
| Description | Adamantanine is a potent inhibitor of leucine aminopeptidase, demonstrating an I/S0.5 value of 10.5. It effectively impairs the transport of methionine and leucine in Ehrlich ascites carcinoma cells, with a Ki value of 0.76 mM. Additionally, Adamantanine displays inhibitory effects on the proliferation of P388 lymphocytic leukemia cells, exhibiting an IC50 of greater than 1 mM. This compound serves as a valuable tool for researchers investigating amino acid transport and cancer cell proliferation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
