Product Data Sheet
Ketomethylenebestatin
Catalog No. A69454
Ketomethylenebestatin is a selective inhibitor of aminopeptidases, showcasing notable activity against AP-B, AP-M, and Leu-AP with IC50 values of 56 μM, 752 μM, and 0.39 μM, respectively. This compound serves as an analog of the natural aminopeptidase inhibitor Bestatin, and is valuable in research applications focused on the regulation of peptide metabolism and potential therapeutic targets in various diseases. Its specificity towards aminopeptidases makes it a useful tool for investigating enzymatic pathways and the role of these enzymes in physiological processes.
Chemical Information
| Catalog Num | A69454 |
|---|---|
| M. Wt | 307.38 |
| Formula | C17H25NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 137028-97-8 |
| Synonyms | |
| SMILES | O=C(C(CC(C)C)CC(C(C(CC1=CC=CC=C1)N)O)=O)O |
Biological Activity
| Description | Ketomethylenebestatin is a selective inhibitor of aminopeptidases, showcasing notable activity against AP-B, AP-M, and Leu-AP with IC50 values of 56 μM, 752 μM, and 0.39 μM, respectively. This compound serves as an analog of the natural aminopeptidase inhibitor Bestatin, and is valuable in research applications focused on the regulation of peptide metabolism and potential therapeutic targets in various diseases. Its specificity towards aminopeptidases makes it a useful tool for investigating enzymatic pathways and the role of these enzymes in physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
