Product Data Sheet
DRL-17822
Catalog No. A69643
DRL-17822 is a selective inhibitor of cholesteryl ester transfer protein (CETP). This compound effectively elevates high-density lipoprotein (HDL) levels, which is key in the management of type II hyperlipidemia and atherosclerotic cardiovascular disease. Notably, the bioavailability of DRL-17822 is enhanced after a high-fat meal, with improved exposure observed in the fasted state compared to its nanocrystal formulation. This makes DRL-17822 a valuable tool for research focused on lipid metabolism and cardiovascular health.
Chemical Information
| Catalog Num | A69643 |
|---|---|
| M. Wt | 603.60 |
| Formula | C30H31F6N7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 898911-09-6 |
| Synonyms | |
| SMILES | FC(F)(C1=CC(CN(CC2=CC3=C(N=C2N(CC4CC4)CC5CC5)C(C)=CC=C3)C6=NN(C)N=N6)=CC(C(F)(F)F)=C1)F |
Biological Activity
| Description | DRL-17822 is a selective inhibitor of cholesteryl ester transfer protein (CETP). This compound effectively elevates high-density lipoprotein (HDL) levels, which is key in the management of type II hyperlipidemia and atherosclerotic cardiovascular disease. Notably, the bioavailability of DRL-17822 is enhanced after a high-fat meal, with improved exposure observed in the fasted state compared to its nanocrystal formulation. This makes DRL-17822 a valuable tool for research focused on lipid metabolism and cardiovascular health. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
