Product Data Sheet
1β-Hydroxydeoxycholic acid
Catalog No. A69735
1β-Hydroxydeoxycholic acid (1β-OH-DCA) is a secondary bile acid and a recognized biomarker for the CYP3A enzyme family. It is primarily generated through the metabolism of deoxycholic acid via CYP3A4 and CYP3A7 employing recombinant human CYP450 enzymes. This compound serves as an important tool in pharmacokinetic studies and the evaluation of drug metabolism, facilitating research in drug interactions and personalized medicine involving CYP3A activity.
Chemical Information
| Catalog Num | A69735 |
|---|---|
| M. Wt | 408.57 |
| Formula | C24H40O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 80434-32-8 |
| Synonyms | 1β-OH-DCA |
| SMILES | C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@@H](C[C@H]2O)O)([H])[C@@]4([H])[C@]([C@H](C3)O)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C |
Biological Activity
| Description | 1β-Hydroxydeoxycholic acid (1β-OH-DCA) is a secondary bile acid and a recognized biomarker for the CYP3A enzyme family. It is primarily generated through the metabolism of deoxycholic acid via CYP3A4 and CYP3A7 employing recombinant human CYP450 enzymes. This compound serves as an important tool in pharmacokinetic studies and the evaluation of drug metabolism, facilitating research in drug interactions and personalized medicine involving CYP3A activity. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
