Product Data Sheet

CYP3A4-IN-2

Catalog No. A69820

main product photo
CYP3A4-IN-2 is a selective inhibitor of cytochrome P450 3A4 (CYP3A4), exhibiting an IC50 value of 0.055 μM. As a ritonavir analogue, it possesses enhanced hydrophobicity in the R2 side group, resulting in a more potent inhibitory effect than ritonavir. This reagent is applicable in research focused on antiviral therapies and immunosuppressive mechanisms.
Chemical Information
Catalog NumA69820
M. Wt570.74
FormulaC33H38N4O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2562383-94-0
Synonyms
SMILESO=C(OC(C)(C)C)NC(CC1=C2C=CC=CC2=CC=C1)CSCC(NC3=CC=CC=C3)C(NCC4=CC=CN=C4)=O
Biological Activity
DescriptionCYP3A4-IN-2 is a selective inhibitor of cytochrome P450 3A4 (CYP3A4), exhibiting an IC50 value of 0.055 μM. As a ritonavir analogue, it possesses enhanced hydrophobicity in the R2 side group, resulting in a more potent inhibitory effect than ritonavir. This reagent is applicable in research focused on antiviral therapies and immunosuppressive mechanisms.
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