Product Data Sheet
Ticlopidine hydrochloride-d6
Catalog No. A69898
Ticlopidine hydrochloride-d6 is a deuterium-labeled derivative of Ticlopidine hydrochloride, functioning primarily as a stable isotope for research applications. Ticlopidine is recognized as an antithrombotic agent and acts as an allosteric, noncompetitive inhibitor of CD39, demonstrating an IC50 of 81.7 μM. Furthermore, it inhibits various NTPDase isoenzymes, with IC50 values of 170 μM for NTPDase2 and 149 μM for NTPDase3, in addition to its role as an inhibitor of CYP2C19, CYP2C9, and CYP3A4, with IC50s of 26.0 and 32.3 μM, respectively. This reagent is valuable for studies involving purinergic signaling and drug metabolism.
Chemical Information
| Catalog Num | A69898 |
|---|---|
| M. Wt | 306.28 |
| Formula | C14H9D6Cl2NS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2985259-58-1 |
| Synonyms | |
| SMILES | ClC1=C(C([2H])=C(C([2H])=C1C([2H])(N2CC3=C(CC2)SC=C3)[2H])[2H])[2H].Cl |
Biological Activity
| Description | Ticlopidine hydrochloride-d6 is a deuterium-labeled derivative of Ticlopidine hydrochloride, functioning primarily as a stable isotope for research applications. Ticlopidine is recognized as an antithrombotic agent and acts as an allosteric, noncompetitive inhibitor of CD39, demonstrating an IC50 of 81.7 μM. Furthermore, it inhibits various NTPDase isoenzymes, with IC50 values of 170 μM for NTPDase2 and 149 μM for NTPDase3, in addition to its role as an inhibitor of CYP2C19, CYP2C9, and CYP3A4, with IC50s of 26.0 and 32.3 μM, respectively. This reagent is valuable for studies involving purinergic signaling and drug metabolism. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
