Product Data Sheet

CYP11B2-IN-3

Catalog No. A69943

main product photo
CYP11B2-IN-3 is a selective inhibitor of CYP11B2, demonstrating an IC50 value of 12.92 nM for CYP11B2 and 2341 nM for CYP11B1. This compound is orally active, making it suitable for in vivo studies. CYP11B2-IN-3 is primarily applicable in research related to hypertension, providing a valuable tool for investigating the role of CYP11B2 in adrenal steroidogenesis and blood pressure regulation.
Chemical Information
Catalog NumA69943
M. Wt394.90
FormulaC22H23ClN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3072732-90-9
Synonyms
SMILESO=C(CC)N[C@H](CCC1)C2=C1C(C3=CC(Cl)=C(C4=CC=NN4C)C=C3)=CN=C2
Biological Activity
DescriptionCYP11B2-IN-3 is a selective inhibitor of CYP11B2, demonstrating an IC50 value of 12.92 nM for CYP11B2 and 2341 nM for CYP11B1. This compound is orally active, making it suitable for in vivo studies. CYP11B2-IN-3 is primarily applicable in research related to hypertension, providing a valuable tool for investigating the role of CYP11B2 in adrenal steroidogenesis and blood pressure regulation.
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