Product Data Sheet

CYP11B2-IN-2

Catalog No. A69957

main product photo
CYP11B2-IN-2 is a potent inhibitor of the aldosterone synthase enzyme CYP11B2, exhibiting an IC50 value of 0.3 nM. This compound is labeled with 18F, enabling its application as a positron emission tomography (PET) tracer for the diagnosis of primary aldosteronism. Its high specificity and efficacy make it a valuable tool for research in endocrine disorders and adrenal function.
Chemical Information
Catalog NumA69957
M. Wt284.29
FormulaC16H13FN2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2241573-22-6
Synonyms
SMILESFC1=CC(C2=CC(C3(C)OCCO3)=CN=C2)=CC=C1C#N
Biological Activity
DescriptionCYP11B2-IN-2 is a potent inhibitor of the aldosterone synthase enzyme CYP11B2, exhibiting an IC50 value of 0.3 nM. This compound is labeled with 18F, enabling its application as a positron emission tomography (PET) tracer for the diagnosis of primary aldosteronism. Its high specificity and efficacy make it a valuable tool for research in endocrine disorders and adrenal function.
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