Product Data Sheet

hDHODH-IN-13

Catalog No. A70034

main product photo
hDHODH-IN-13 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH), with an IC50 value of 173.4 nM. This compound demonstrates significant potential in the investigation of inflammatory bowel disease (IBD) by modulating pyrimidine biosynthesis. hDHODH-IN-13 is a valuable tool for exploring therapeutic strategies targeting hDHODH in various disease models.
Chemical Information
Catalog NumA70034
M. Wt393.84
FormulaC21H17ClFN5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3032611-13-2
Synonyms
SMILESNC1=NC(C2=CN(CC3=C(F)C=CC=C3Cl)C4=NC=CC=C42)=NC=C1C5CC5
Biological Activity
DescriptionhDHODH-IN-13 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH), with an IC50 value of 173.4 nM. This compound demonstrates significant potential in the investigation of inflammatory bowel disease (IBD) by modulating pyrimidine biosynthesis. hDHODH-IN-13 is a valuable tool for exploring therapeutic strategies targeting hDHODH in various disease models.
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