Product Data Sheet
4-Hydroxymethylpyrazole
Catalog No. A70143
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, produced via hepatic oxidative metabolism. This compound exhibits a plasma concentration that correlates with the administered dosage of Fomepizole and has a relatively short half-life. It acts as an inhibitor of alcohol dehydrogenase (ADH) in humans and monkeys; however, its inhibition constant is significantly higher than that of its parent compound, suggesting a minimal in vivo impact. It is primarily used for research on metabolic pathways and drug interactions.
Chemical Information
| Catalog Num | A70143 |
|---|---|
| M. Wt | 98.11 |
| Formula | C4H6N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 25222-43-9 |
| Synonyms | |
| SMILES | OCC1=CNN=C1 |
Biological Activity
| Description | 4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, produced via hepatic oxidative metabolism. This compound exhibits a plasma concentration that correlates with the administered dosage of Fomepizole and has a relatively short half-life. It acts as an inhibitor of alcohol dehydrogenase (ADH) in humans and monkeys; however, its inhibition constant is significantly higher than that of its parent compound, suggesting a minimal in vivo impact. It is primarily used for research on metabolic pathways and drug interactions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
