Product Data Sheet
Niraparib metabolite M1
Catalog No. A70153
Niraparib metabolite M1 is a bioactive metabolite of the poly(ADP-ribose) polymerase (PARP) inhibitor niraparib. This compound retains the biological effects associated with PARP inhibition, contributing to the understanding of niraparib's pharmacokinetics and pharmacodynamics. Niraparib metabolite M1 is relevant for investigating the mechanisms of action and therapeutic effects of PARP inhibitors in cancer research, particularly in the context of DNA repair and cellular response to genotoxic stress.
Chemical Information
| Catalog Num | A70153 |
|---|---|
| M. Wt | 321.37 |
| Formula | C19H19N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1476777-06-6 |
| Synonyms | Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib |
| SMILES | O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)O |
Biological Activity
| Description | Niraparib metabolite M1 is a bioactive metabolite of the poly(ADP-ribose) polymerase (PARP) inhibitor niraparib. This compound retains the biological effects associated with PARP inhibition, contributing to the understanding of niraparib's pharmacokinetics and pharmacodynamics. Niraparib metabolite M1 is relevant for investigating the mechanisms of action and therapeutic effects of PARP inhibitors in cancer research, particularly in the context of DNA repair and cellular response to genotoxic stress. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
