Product Data Sheet
Ivabradine metabolite N-Demethyl Ivabradine hydrochloride
Catalog No. A70230
N-Demethyl Ivabradine hydrochloride is a metabolite of Ivabradine, targeting the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound exhibits significant activity in modulating cardiac rhythm by inhibiting the funny current (If), making it relevant for research in cardiovascular physiology and pharmacology. Its role in understanding drug metabolism and pharmacokinetics enhances its utility in studies related to cardiovascular diseases and treatment responses.
Chemical Information
| Catalog Num | A70230 |
|---|---|
| M. Wt | 491.02 |
| Formula | C26H35ClN2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1246638-08-3 |
| Synonyms | N-Demethyl ivabradine hydrochloride |
| SMILES | O=C1N(CCCNC[C@@H]2C(C=C(OC)C(OC)=C3)=C3C2)CCC4=CC(OC)=C(OC)C=C4C1.[H]Cl |
Biological Activity
| Description | N-Demethyl Ivabradine hydrochloride is a metabolite of Ivabradine, targeting the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. This compound exhibits significant activity in modulating cardiac rhythm by inhibiting the funny current (If), making it relevant for research in cardiovascular physiology and pharmacology. Its role in understanding drug metabolism and pharmacokinetics enhances its utility in studies related to cardiovascular diseases and treatment responses. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
