Product Data Sheet

16α-Hydroxyprednisolone

Catalog No. A70264

main product photo
16α-Hydroxyprednisolone is a stereoselective metabolite of the glucocorticoid Budesonide, specifically the 22(R) epimer. It is formed through the catalytic action of isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. This compound serves as a valuable tool in studies related to drug metabolism and pharmacokinetics, allowing researchers to investigate the enzymatic pathways and potential inhibitory effects of specific antibodies on CYP3A enzymes.
Chemical Information
Catalog NumA70264
M. Wt376.44
FormulaC21H28O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.13951-70-7
SynonymsOH-PRED
SMILESO=C1C=C[C@@]2([C@]3([C@H](C[C@@]4([C@](O)([C@@H](C[C@]4([C@@]3(CCC2=C1)[H])[H])O)C(CO)=O)C)O)[H])C
Biological Activity
Description16α-Hydroxyprednisolone is a stereoselective metabolite of the glucocorticoid Budesonide, specifically the 22(R) epimer. It is formed through the catalytic action of isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. This compound serves as a valuable tool in studies related to drug metabolism and pharmacokinetics, allowing researchers to investigate the enzymatic pathways and potential inhibitory effects of specific antibodies on CYP3A enzymes.
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SHIPPING AND STORAGE
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