Product Data Sheet

(Rac)-3′-Hydroxy simvastatin

Catalog No. A70313

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(Rac)-3′-Hydroxy simvastatin is a drug metabolite derived from Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase. With a Ki value of 0.2 nM, it plays a crucial role in cholesterol biosynthesis regulation. This compound is relevant in pharmacokinetic studies and investigations into the metabolic pathways of statins.
Chemical Information
Catalog NumA70313
M. Wt434.57
FormulaC25H38O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.126313-98-2
Synonyms
SMILESCC(O)C(C)(C)C(OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(O3)=O)C12)=O
Biological Activity
Description(Rac)-3′-Hydroxy simvastatin is a drug metabolite derived from Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase. With a Ki value of 0.2 nM, it plays a crucial role in cholesterol biosynthesis regulation. This compound is relevant in pharmacokinetic studies and investigations into the metabolic pathways of statins.
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