Product Data Sheet
Bodipy C12-ceramide
Catalog No. A70352
Bodipy C12-ceramide (B12Cer) is a fluorescently labeled derivative of C12-Ceramide, characterized by excitation and emission maxima at 505 nm and 540 nm, respectively. This compound is formed through the hydrolysis of BODIPY-C12 sphingomyelin by acid sphingomyelinase in vitro. Bodipy C12-ceramide is primarily utilized for quantifying acid sphingomyelinase activity in plasma samples, particularly in studies related to Niemann-Pick disease, facilitating insights into sphingolipid metabolism and associated pathologies.
Chemical Information
| Catalog Num | A70352 |
|---|---|
| M. Wt | 713.83 |
| Formula | C42H70BF2N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1246355-58-7 |
| Synonyms | |
| SMILES | CC1=CC(C)=[N+]2C1=C(CCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO)=O)C3=C(C)C=C(C)N3[B-]2(F)F |
Biological Activity
| Description | Bodipy C12-ceramide (B12Cer) is a fluorescently labeled derivative of C12-Ceramide, characterized by excitation and emission maxima at 505 nm and 540 nm, respectively. This compound is formed through the hydrolysis of BODIPY-C12 sphingomyelin by acid sphingomyelinase in vitro. Bodipy C12-ceramide is primarily utilized for quantifying acid sphingomyelinase activity in plasma samples, particularly in studies related to Niemann-Pick disease, facilitating insights into sphingolipid metabolism and associated pathologies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
