Product Data Sheet
11-Desethyl Irinotecan
Catalog No. A70388
11-Desethyl Irinotecan is a camptothecin (CPT) analog and a significant metabolite of irinotecan, targeting topoisomerase I. This compound exhibits potent antitumor activity and is instrumental in cancer research, offering insights into therapeutic applications and metabolism of CPT derivatives. Its pharmacological profile makes it a valuable tool for studying mechanisms of chemotherapy resistance and evaluating efficacy in various cancer models.
Chemical Information
| Catalog Num | A70388 |
|---|---|
| M. Wt | 558.62 |
| Formula | C31H34N4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 103816-16-6 |
| Synonyms | |
| SMILES | O=C1N2C(C(C(C2)=CC3=C4)=NC3=CC=C4OC(N5CCC(N6CCCCC6)CC5)=O)=CC7=C1COC([C@]7(O)CC)=O |
Biological Activity
| Description | 11-Desethyl Irinotecan is a camptothecin (CPT) analog and a significant metabolite of irinotecan, targeting topoisomerase I. This compound exhibits potent antitumor activity and is instrumental in cancer research, offering insights into therapeutic applications and metabolism of CPT derivatives. Its pharmacological profile makes it a valuable tool for studying mechanisms of chemotherapy resistance and evaluating efficacy in various cancer models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
